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溫峰特聘教授

學(xué)歷學(xué)位：博士

政治面貌：無黨派人士

導(dǎo)師類別：碩士生導(dǎo)師

電子郵箱：wenf@fosu.edu.cn

學(xué)習(xí)與工作經(jīng)歷

2005.09-2010.07：吉林大學(xué)，動物醫(yī)學(xué)專業(yè)本科生,；
2010.09-2013.07：中國農(nóng)業(yè)科學(xué)院上海獸醫(yī)研究所,，預(yù)防獸醫(yī)專業(yè)碩士研究生；
2013.08-2018.07：Mississippi State University,，獸醫(yī)學(xué)專業(yè)博士研究生,；
2019.05-至今：佛山科學(xué)技術(shù)學(xué)院。

研究方向

從事動物流感病毒相關(guān)基礎(chǔ)與應(yīng)用研究工作,，主要包括流感病毒與宿主細(xì)胞互作相關(guān)分子機制,、病毒疫苗的研制、病毒跨種傳播機制等研究,。兼任國際SCI學(xué)術(shù)期刊《Frontiers in Immunology》,、《BMC Veterinary Research》和《PLoS One》的編委。

獲獎及榮譽

1.2022年獲得佛山科學(xué)技術(shù)學(xué)院“優(yōu)秀研究生導(dǎo)師”稱號,；
2.Hall of Fame Scholar, Mississippi State University, 2018,；

教學(xué)工作

講授本科生課程《獸醫(yī)生物制品學(xué)》、《生物制品技術(shù)》,、《文獻檢索與論文寫作》等課程,。

教學(xué)及科研項目

1. 主持國家自然科學(xué)基金，青年項目,，32002320,，24萬。
2. 主持省自然科學(xué)基金,，面上項目，2022A1515012462,，10萬,。
3. 主持省自然科學(xué)基金，面上項目,，2020A1515010116,，10萬。
4. 主持省教育廳科研項目,，特色創(chuàng)新,，2022KTSCX124，6萬,。
5. 佛山科學(xué)技術(shù)學(xué)院動物新發(fā)疫病防控重點實驗室開放基金,，10萬。
6. 佛山科學(xué)技術(shù)學(xué)院高層次人才啟動基金,，50萬,。
7. 佛山市博士后啟動基金,，30萬。
8. 廣東省醫(yī)學(xué)科研基金,，青年基金,，A2020083，1萬,。
參與多項國自然基金與美國國立衛(wèi)生研究院基金項目

代表性文章

1.Wen F, S. Blackmon, A. K. Olivier, L. Li, M. Guan, H. Sun, P. G. Wang, and X.-F. Wan. Mutation W222L at the receptor binding site of hemagglutinin could facilitate viral adaption from equine influenza A(H3N8) virus to dogs. Journal of Virology, 2018. 92(18). doi: 10.1128/JVI.01115-18.
2.Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF. A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 influenza A Virus in Cells. Journal of Virology. 2017.92(2). pii: e01621-17.
3.Wen F, and X.-F. Wan. 2019. Influenza Neuraminidase: Underrated Role in Receptor Binding. Trends in Microbiology, 2019. 27(6): p. 477-479.
4.Guo J, Yu H, Wang C, Yuan S, Sun H, Yang J, Cheng Q, Luo K, Li Y, Li Z, Liu Q, Huang S, Wen F. 2021. Re-emergence of highly pathogenic avian influenza A(H5N8) virus in domestic Goose, China. J Infect 83:709-737.
5.Yu Y, Wu M, Cui X, Xu F, Wen F, Pan L, Li S, Sun H, Zhu X, Lin J, Feng Y, Li M, Liu Y, Yuan S, Liao M, Sun H. 2021. Pathogenicity and transmissibility of current H3N2 swine influenza virus in Southern China: A zoonotic potential. Transbound Emerg Dis doi:10.1111/tbed.14190.
6.Guo J, Wang C, Huang S, Wen F. 2021. Sequencing bias for residue 28 of the neuraminidase of the recent highly pathogenic avian influenza virus A(H5N8). Euro Surveill 26.
7.Wen F, Li W, Guo J, Yang J, Zhang X, Mei K, Liu H, El-Ashram S, Luo K, Yuan S, Chi S, Huang S. 2020. Genetic characterization of a novel genotype H9N2 avian influenza virus from chicken in South China. J Infect doi:10.1016/j.jinf.2020.09.011.
8.Wen F, Yu H, Guo J, Li Y, Luo K, Huang S. 2020. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2. J Infect doi:10.1016/j.jinf.2020.02.027.
9.Wen F, Huang S and Guo J. Egg adaptive mutation patterns of H3N2 human influenza A viruses. J Infect. 2019. 80:232-254.
10.Guo J, Huang S and Wen F. Identification of coevolution sites and evolution history for neuraminidase of human influenza A viruses. J Infect. 2019. Oct 18. PubMed PMID: 31634491. Epub 2019/10/22doi.org/10.1016/j.jinf.2019.10.012.
11.Ruan BY#, Wen F#, Gong XQ, Liu XM, Wang Q, Yu LX, Zhang P, Wang SY, Yang HM, Shan TL, Zheng H, Zhou YJ, Tong W, Li GX, Gao F, Jiang YF, Tong GZ, Yu H. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs. Veterinary Microbiology. 2018. 222:75-84.
12.Wen F., Guo, JY, Li zhili, Huang, SJ. Sex-specific patterns of gene expression following influenza vaccination. Scientific Reports, 2018. 8(1): p. 13517.
13. Wen F, Chen G, Guo J, Guan M, Li Z, Yu H, Li J, Liu Q, Huang S. Identification of a duck H9N2 influenza virus possessing tri-basic hemagglutinin cleavage sites genetically close to the human H9N2 isolates in China, 2022. J Infect. 2023 Jun;86(6):e153-e155.
14. Zhang X, Wen F. Recent advances in Reovirales viruses reverse genetics research. Virus Res. 2022 Nov;321:198911.
15. Yuan S, Cheng Q, Guo J, Li Z, Yang J, Wang C, Liang Z, Zhang X, Yu H, Li Y, Huang S, Wen F. Detection and genetic characterization of novel infectious bronchitis viruses from recent outbreaks in broiler and layer chicken flocks in southern China, 2021. Poult Sci. 2022 Oct;101(10):102082.
16. Guan M, Olivier AK, Lu X, Epperson W, Zhang X, Zhong L, Waters K, Mamaliger N, Li L, Wen F, Tao YJ, DeLiberto TJ, Wan XF. The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses. J Virol. 2022 Oct 12;96(19):e0134422.
17. Wang SY#, Wen F#, Yu LX, Wang J, Wang MZ, Yan JC, Zhou YJ, Tong W, Shan TL, Li GX, Zheng H, Liu CL, Kong N, Tong GZ, Yu H. Potential Threats to Human Health from Eurasian Avian-Like Swine Influenza A(H1N1) Virus and Its Reassortants. Emerg Infect Dis. 2022 Jul;28(7):1489-1493. doi: 10.3201/eid2807.211822. Epub 2022 Jun 9. PMID: 35680129; PMCID: PMC9239861.
18. Han L, Li L, Wen F, Zhong L, Zhang T, Wan XF. Graph-guided multi-task sparse learning model: a method for identifying antigenic variants of influenza A(H3N2) virus. Bioinformatics. 2019 Jan 1;35(1):77-87.
19. Sun H, Blackmon S, Yang G, Waters K, Li T, Tangwangvivat R, Xu Y, Shyu D, Wen F, Cooley J, Senter L, Lin X, Jarman R, Hanson L, Webby R, Wan XF. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. J Virol. 2017 Oct 13;91(21):e00637-17.

其他成果

INFLUENZA VIRUS VACCINE AND METHOD OF MAKING,，PCT專利，WO/2018/201044, 2018.04
檢測禽流感病毒H3,、H4和H5亞型的熒光定量PCR引物探針組及試劑盒, 國家發(fā)明專利,，202211490380.2，2022.11