陳吾雅簡(jiǎn)介

陳吾雅

男，理學(xué)博士，口腔系,，特聘青年研究員

研究方向：1. 仿生生物醫(yī)用材料

2. 干細(xì)胞與組織工程

3. 口腔疾病與納米材料

2018年7月畢業(yè)于華南師范大學(xué)生命科學(xué)學(xué)院,，細(xì)胞生物學(xué)專業(yè)，細(xì)胞信號(hào)轉(zhuǎn)導(dǎo)方向,。博士研究生期間主要從事生物材料與組織工程領(lǐng)域的基礎(chǔ)理論研究,。

現(xiàn)為佛山科學(xué)技術(shù)學(xué)院口腔醫(yī)學(xué)院特聘青年研究員，開展生物材料相關(guān)研究工作,。主要采用組織工程學(xué)研究策略,，設(shè)計(jì)和制備多種仿生生物材料治療口腔相關(guān)疾病，如牙髓炎,、齲病,、顱頜面創(chuàng)傷等。并研究治療與修復(fù)過(guò)程涉及的細(xì)胞和分子學(xué)機(jī)理,。

當(dāng)前,，以第一作者身份發(fā)表SCI論文2篇，參與SCI論文發(fā)表13篇,，授權(quán)國(guó)家發(fā)明專利1項(xiàng),。博士研究生期間，參與導(dǎo)師主持國(guó)家或省部級(jí)課題多項(xiàng),。2016年獲得博士研究生國(guó)家獎(jiǎng)學(xué)金,。

發(fā)表論文：

1. Q. Ban, W.
   Chen, S. Du, H. Wang, J. Li, R. You, Y. Jin, Y. Xue, Y.Q. Guan, The
   preparation of the ordered pores colloidal crystal scaffold and its role in
   promoting growth of lung cells, Colloids
   Surfaces B Biointerfaces. 173 (2019) 907–917.

2. W. Chen, W.
   Wang, L. Chen, J. Chen, X. Lu, Z. Li, B. Wu, L. Yin, Y.Q. Guan, Long-term
   G1cell cycle arrest in cervical cancer cells induced by co-immobilized TNF-α
   plus IFN-γ polymeric drugs, J. Mater.
   Chem. B. 6 (2018) 327–336.

3. K. Hu, X. Chen, W. Chen, L. Zhang, J. Li, J. Ye, Y. Zhang, L. Zhang, C.H. Li, L.
   Yin, Y.Q. Guan, Neuroprotective effect of gold nanoparticles composites in
   Parkinson’s disease model, Nanomedicine
   Nanotechnology, Biol. Med. 14 (2018) 1123–1136.

4. L. Yin, Z. Meng, Y. Zhang, K. Hu, W. Chen, K. Han, B.Y. Wu, R. You, C.H.
   Li, Y. Jin, Y.Q. Guan, Bacillus spore-based oral carriers loading curcumin for
   the therapy of colon cancer, J. Control.
   Release. 271 (2018) 31–44.

5. L.K. Zhang, H. Wang, R. Yang, M. Liu, Q. Ban, W. Chen, M. Zhao, R. You, Y. Jin, Y.Q.
   Guan, Bone marrow stem cells combined with polycaprolactone-polylactic
   acid-polypropylene amine scaffolds for the treatment of acute liver failure, Chem. Eng. J. 360 (2018) 1564–1576.

6. S.W. Du, L.K. Zhang, K. Han, S. Chen, Z. Hu, W. Chen, K. Hu, L. Yin, B. Wu, Y.Q.
   Guan, Combined Phycocyanin and Hematoporphyrin Monomethyl Ether for Breast
   Cancer Treatment via Photosensitizers Modified Fe3O4Nanoparticles Inhibiting
   the Proliferation and Migration of MCF-7 Cells, Biomacromolecules. 19 (2018) 31–41.

7. M. Zhao, L. Chen, W. Chen, Z. Meng, K. Hu, S. Du, L. Zhang, L. Yin, B. Wu, Y.-Q.
   Guan, Packaging cordycepin phycocyanin micelles for the inhibition of brain
   cancer, J. Mater. Chem. B. 5 (2017)
   6016–6026.

8. L. Zhang, Y.X. Zhang, J.N. Qiu, J. Li, W. Chen, Y.Q. Guan, Preparation and
   Characterization of Hypoglycemic Nanoparticles for Oral Insulin Delivery, Biomacromolecules. 18 (2017) 4281–4291.

9. S. Niu, L.K. Zhang, L. Zhang, S. Zhuang, X. Zhan, W.Y. Chen, S. Du, L. Yin, R. You, C.H.
   Li, Y.Q. Guan, Inhibition by multifunctional magnetic nanoparticles loaded with
   alpha-synuclein RNAi plasmid in a Parkinson’s disease model, Theranostics. 7 (2017) 344–356.

10. W.Y. Chen, R.C.
    Yang, H.M. Wang, L. Zhang, K. Hu, C.H. Li, R. You, L. Yin, Y.Q. Guan,
    Self-Assembled Heterojunction Carbon Nanotubes Synergizing with
    Photoimmobilized IGF-1 Inhibit Cellular Senescence, Adv. Healthc. Mater. 5 (2016) 2413–2426.

11. L. Zhang, W. Cai, W.Y. Chen, L. Zhang, K. Hu, Y.Q. Guan, Synthesis of AzPhchitosan-bifenthrin-PVC
    to protect cables against termites, Carbohydr.
    Polym. 139 (2016) 50–60.

12. L. Wu, K. Hu, L. Zhang, W. Chen, X. Chen, R. You, L. Yin, Y.Q. Guan, Preparation and
    characterization of latex films photo-immobilized with IFN-α, Colloids Surfaces B Biointerfaces. 145
    (2016) 104–113.

13. R. Yang, L. Wu, J. Chen, W. Chen, L. Zhang, L. Zhang, R. You, L. Yin, C.H. Li, Y.Q. Guan,
    Effects of Differentiation and Antisenescence from BMSCs to Hepatocy-Like Cells
    of the PAAm-IGF-1/TNF-α Biomaterial, ACS
    Appl. Mater. Interfaces. 8 (2016) 26638–26647.

授權(quán)專利：

1. 關(guān)燕清，劉俊明,，陳吾雅,。一種抗細(xì)胞衰老的骨組織工程支架材料及其應(yīng)用。專利號(hào)201410173890.6