溫峰（碩士生導(dǎo)師）

姓名：溫峰                   

職稱：教授

學(xué)歷學(xué)位：博士研究生

政治面貌： 無黨派人士

導(dǎo)師類別： 碩士生導(dǎo)師

電子郵箱： [email protected]

學(xué)習(xí)與工作經(jīng)歷：

2005-2010，吉林大學(xué)畜牧獸醫(yī)學(xué)院，動(dòng)物醫(yī)學(xué)，學(xué)士；導(dǎo)師：張乃生 教授。

2010-2013，中國(guó)農(nóng)業(yè)科學(xué)院上海獸醫(yī)研究所，預(yù)防獸醫(yī)學(xué)，碩士；導(dǎo)師：童光志 研究員。

2013-2019，美國(guó)Mississippi State University獸醫(yī)學(xué)院，獸醫(yī)學(xué)，博士、博士后；導(dǎo)師：萬秀峰 教授。

2019年至今，佛山大學(xué)，動(dòng)物科技學(xué)院，獸醫(yī)系，特聘教授、教授、嶺南學(xué)者。

研究方向：從事動(dòng)物流感病毒相關(guān)基礎(chǔ)與應(yīng)用研究工作，主要包括流感病毒與宿主細(xì)胞互作相關(guān)分子機(jī)制、病毒疫苗的研制、病毒跨種傳播機(jī)制等研究。

獲獎(jiǎng)及榮譽(yù)：

Hall of Fame Scholar, Mississippi State University, 2018

“優(yōu)秀研究生導(dǎo)師”，佛山科學(xué)技術(shù)學(xué)院，2022

“嶺南學(xué)者”

指導(dǎo)第九屆全國(guó)大學(xué)生生命科學(xué)競(jìng)賽（科學(xué)探究類）三等獎(jiǎng)，2024

第33屆廣東省畜牧獸醫(yī)科技大會(huì)“永順杯”優(yōu)秀論文，2024

教學(xué)工作：承擔(dān)《獸醫(yī)分子病毒學(xué)》、《分子生物學(xué)》、《獸醫(yī)生物制品技術(shù)》、等課程。

教學(xué)及科研項(xiàng)目：

1. 主持國(guó)家自然科學(xué)基金，青年項(xiàng)目，32002320，24萬。

2. 主持省自然科學(xué)基金，面上項(xiàng)目，2024A1515010836，15萬。

3. 主持省自然科學(xué)基金，面上項(xiàng)目，2022A1515012462，10萬。

4. 主持省自然科學(xué)基金，面上項(xiàng)目，2020A1515010116，10萬。

5. 主持省教育廳科研項(xiàng)目，特色創(chuàng)新，2022KTSCX124，6萬。

6. 佛山科學(xué)技術(shù)學(xué)院動(dòng)物新發(fā)疫病防控重點(diǎn)實(shí)驗(yàn)室開放基金，10萬。

7. 佛山科學(xué)技術(shù)學(xué)院高層次人才啟動(dòng)基金，50萬。

8. 佛山市博士后啟動(dòng)基金，30萬。

9. 廣東省醫(yī)學(xué)科研基金，青年基金，A2020083，1萬。

10. 農(nóng)業(yè)農(nóng)村部禽流感等家禽重大疾病防控重點(diǎn)實(shí)驗(yàn)室開放課題，5萬。

代表性文章 第一作者（或共同第一作者）和通訊作者（或共同通訊作者）：

以第一或通訊作者（含共同）在Science、Lancet Microbe、Trends in Microbiology、Nature Communications、Journal of Infection(9)、mBio、Emerging Microbes & Infections、Journal of Virology(4)、Emerging Infectious Diseases、Eurosurveillance、Virulence、Virology、Veterinary Microbiology (2)、Poultry Science(4)、Virus Research和Archives of Virology等主流期刊共發(fā)表SCI論文三十余篇。

2025 

Wen F, Guo J, Li Y, Yu H, Zhang K, Ren T, Huang S. Evolving H5N1 receptor specificity. Science. 2025. 10.1126 (In press).

2024

Wen F, Yang Y, Li Y, Guo J, Li Z, Liu L, Liu H, Mei K, Qin L, Zhang K, Ren T, Huang S. Novel human-type receptor-binding H5N1 virus in live poultry markets, China. Lancet Microbe. 2024 Dec 10:101049.

Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J, Yu H, Liu Q, Huang S. 2024. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol 10.1128/jvi.00248-24.

Guo J, He J, Liang Z, Huang S, Wen F. 2024. Birds as reservoirs: unraveling the global spread of Gammaand Deltacoronaviruses. mBio 10.1128/mbio.02324-24.

Gao C, Wen F, Guan M, Hatuwal B, Li L, Praena B, Tang CY, Zhang J, Luo F, Xie H, Webby R, Tao YJ, Wan XF. 2024. MAIVeSS: streamlined selection of antigenically matched, high-yield viruses for seasonal influenza vaccine production. Nat Commun 15:1128.

He J, Liu J, Yan Z, Chen G, Liu R, Yang Y, Yan Y, Yuan S, Guo J, Li Y, Yu H, Liang Z, Ren T, Huang S, Wen F. Genetic characterization and receptor binding analysis of a novel H5N1 HPAI virus with a H6Nx-derived PA gene in Guangdong, China. Emerg Microbes Infect. 2024 Dec;13(1):2417857.

Zhang X, Chen G, Liu R, Guo J, Mei K, Qin L, Li Z, Yuan S, Huang S, Wen F. 2024. Identification, pathological, and genomic characterization of novel goose reovirus associated with liver necrosis in geese, China. Poult Sci 103:103269.

Wen F, Wang C, Guo J, Yu H, Yuan S, Li Y, Li Z, Huang S, Liang Z. 2024. Development and application of a triplex real-time PCR assay for the detection of H3, H4, and H5 subtypes of avian influenza virus. Poult Sci 103:103333.

Liu J, Liang Z, Sun W, Hua W, Huang S, Wen F. The H4 subtype of avian influenza virus: a review of its historical evolution, global distribution, adaptive mutations and receptor binding properties. Poult Sci. 2024 Aug;103(8):103913. 

2023

Yan Z, Li Y, Huang S, Wen F. 2023. Global distribution, receptor binding, and cross-species transmission of H6 influenza viruses: risks and implications for humans. J Virol 97:e0137023.

Wen F, Chen G, Guo J, Guan M, Li Z, Yu H, Li J, Liu Q, Huang S. 2023. Identification of a duck H9N2 influenza virus possessing tri-basic hemagglutinin cleavage sites genetically close to the human H9N2 isolates in China, 2022. J Infect 86:e153-e155.

Liu L, Chen G, Huang S, Wen F. 2023. Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research Advances. Virulence 14:2235459.

2022

Yuan S, Cheng Q, Guo J, Li Z, Yang J, Wang C, Liang Z, Zhang X, Yu H, Li Y, Huang S, Wen F. 2022. Detection and genetic characterization of novel infectious bronchitis viruses from recent outbreaks in broiler and layer chicken flocks in southern China, 2021. Poult Sci 101:102082.

Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Yu H, Du Y, Huang S, Li J, Li Y. 2022. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect 85:e112-e114.

Wang SY, Wen F, Yu LX, Wang J, Wang MZ, Yan JC, Zhou YJ, Tong W, Shan TL, Li GX, Zheng H, Liu CL, Kong N, Tong GZ, Yu H. 2022. Potential Threats to Human Health from Eurasian Avian-Like Swine Influenza A(H1N1) Virus and Its Reassortants. Emerg Infect Dis 28:1489-1493.

Zhang X, Wen F. Recent advances in Reovirales viruses reverse genetics research. Virus Res. 2022 Nov;321:198911.

Liang Z, Guo J, Yuan S, Cheng Q, Zhang X, Liu Z, Wang C, Li Z, Hou B, Huang S, Wen F. Pathological and Molecular Characterization of a Duck Plague Outbreak in Southern China in 2021. Animals. 2022 Dec 13;12(24):3523.

2021

Guo J, Wang C, Huang S, Wen F. Letter to the editor: Sequencing bias for residue 28 of the neuraminidase of the recent highly pathogenic avian influenza virus A(H5N8). Euro Surveill. 2021 Sep;26(36):2100829. doi: 10.2807/1560-7917.

Yang J, Li Y, Guo J, Luo K, Yu H, Chen Y, Li A, Yuan S, El-Ashram S, Huang S, Wen F. 2021. Genetic characterization of an H5N6 avian influenza virus from chickens in Guangdong, China. J Infect 82:414-451.

Guo J, Yu H, Yang J, Li Y, Zhang X, Mei K, Chi S, Yuan S, Liu H, El-Ashram S, Huang S, Wen F. 2021. Weighted gene co-expression network analysis revealed host transcriptional response to H1N1 influenza A virus infection. J Infect 82:e4-e7.

Guo J, Yu H, Wang C, Yuan S, Sun H, Yang J, Cheng Q, Luo K, Li Y, Li Z, Liu Q, Huang S, Wen F. 2021. Re-emergence of highly pathogenic avian influenza A(H5N8) virus in domestic Goose, China. J Infect 83:709-737.

Wen F, Yang J, Li A, Gong Z, Yang L, Cheng Q, Wang C, Zhao M, Yuan S, Chen Y, El-Ashram S, Li Y, Yu H, Guo J, Huang S. Genetic characterization and phylogenetic analysis of porcine epidemic diarrhea virus in Guangdong, China, between 2018 and 2019. PLoS One. 2021 Jun 24;16(6):e0253622.

2020

Wen F, Yu H, Guo J, Li Y, Luo K, Huang S. 2020. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2. J Infect 80:671-693.

Wen F, Li W, Guo J, Yang J, Zhang X, Mei K, Liu H, El-Ashram S, Luo K, Yuan S, Chi S, Huang S. 2020. Genetic characterization of a novel genotype H9N2 avian influenza virus from chicken in South China. J Infect 81:816-846.

Wen F, Huang S, Guo J. 2020. Egg adaptive mutation patterns of H3N2 human influenza A viruses. J Infect 80:232-254.

Wang XH, Gong XQ, Wen F, Ruan BY, Yu LX, Liu XM, Wang Q, Wang SY, Wang J, Zhang YF, Zhou YJ, Shan TL, Tong W, Zheng H, Kong N, Yu H, Tong GZ. 2020. The role of PA-X C-terminal 20 residues of classical swine influenza virus in its replication and pathogenicity. Vet Microbiol 251:108916.

Guo J, Huang S, Wen F. 2020. Identification of coevolution sites and evolution history for neuraminidase of human influenza A viruses. J Infect 80:232-254. 

2019

Wen F, Wan XF. 2019. Influenza Neuraminidase: Underrated Role in Receptor Binding. Trends Microbiol 27:477-479.

Wen F, Guo J, Huang S. 2019. A meta-analysis identified genes responsible for distinct immune responses to trivalent inactivated and live attenuated influenza vaccines. J Cell Physiol 234:5196-5202.

2018

Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF. 2018. A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells. J Virol 92.(2):e01621-17.

Wen F, Blackmon S, Olivier AK, Li L, Guan M, Sun H, Wang PG, Wan XF. 2018. Mutation W222L at the Receptor Binding Site of Hemagglutinin Could Facilitate Viral Adaption from Equine Influenza A(H3N8) Virus to Dogs. J Virol 92(18):e01115-18.

Ruan BY, Wen F, Gong XQ, Liu XM, Wang Q, Yu LX, Wang SY, Zhang P, Yang HM, Shan TL, Zheng H, Zhou YJ, Tong W, Gao F, Tong GZ, Yu H. 2018. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs. Vet Microbiol 222:75-84.

社會(huì)兼職：

佛山科學(xué)技術(shù)學(xué)院知聯(lián)會(huì)副會(huì)長(zhǎng)

Frontiers in Immunology（二區(qū)）、BMC Veterinary Research（二區(qū)）、Virology Journal（三區(qū)）和PLoS One（三區(qū)）雜志編委

中國(guó)畜牧獸醫(yī)學(xué)會(huì)高級(jí)會(huì)員

世界家禽學(xué)會(huì)會(huì)員

美國(guó)病毒學(xué)會(huì)會(huì)員

美國(guó)糖生物學(xué)會(huì)會(huì)員

廣東省畜牧獸醫(yī)學(xué)會(huì)會(huì)員

廣東省科技咨詢專家?guī)斐蓡T

廣東省高層次人才評(píng)審專家?guī)斐蓡T

佛山市青少年科技創(chuàng)新大賽專家?guī)欤u(píng)審專家

國(guó)家自然科學(xué)基金與廣東省自然科學(xué)基金評(píng)審專家?guī)斐蓡T