溫峰(碩士生導師)
姓名:溫峰
性別: 男
職稱:佛山大學 教授
個人榮譽:
Hall of Fame Scholar, Mississippi State University, 2018;
“優(yōu)秀研究生導師”,,佛山科學技術學院,,2022;
教育與工作簡歷:
2010年畢業(yè)于吉林大學畜牧獸醫(yī)學院,獲學士學位,;導師:張乃生 教授。
2013年畢業(yè)于中國農(nóng)業(yè)科學院上海獸醫(yī)研究所,,獲碩士學位,;導師:童光志 研究員,。
2018年畢業(yè)于美國Mississippi State University獸醫(yī)學院,獲哲學博士學位,;導師:萬秀峰 教授,。
2019年至今,佛山大學,,生命科學與工程學院,,獸醫(yī)系,特聘教授,、教授,、嶺南學者。
主要研究內(nèi)容和研究成果
從事動物流感病毒相關基礎與應用研究工作,,主要包括流感病毒與宿主細胞互作相關分子機制,、病毒疫苗的研制、病毒跨種傳播機制等研究,。以第一或通訊作者(含共同)在Journal of Infection(9篇),、Nature Communications (1篇)、Journal of Virology(4篇),、Trends in Microbiology(1篇),、mBio(1篇)、Emerging Infectious Diseases(1篇),、Eurosurveillance(1篇),、Virulence(1篇)和Poultry Science(4篇)等主流權(quán)威期刊共發(fā)表SCI論文三十余篇。
教學與人才培養(yǎng):
承擔《獸醫(yī)生物制品學》,、《生物制品技術》等課程,。
社會兼職:
佛山科學技術學院知聯(lián)會副會長
Virology Journal(三區(qū),IF2022=5.9)Associate editor
Frontiers in Immunology(二區(qū),,IF2022=8.7),、BMC Veterinary Research(二區(qū),IF2022=2.7)和PLoS ONE(三區(qū),,IF2022=3.7)Editor
中國畜牧獸醫(yī)學會高級會員
世界家禽學會會員
美國病毒學會會員
美國糖生物學會會員
廣東省畜牧獸醫(yī)學會會員
廣東省科技咨詢專家?guī)斐蓡T
廣東省高層次人才評審專家?guī)斐蓡T
佛山市青少年科技創(chuàng)新大賽專家?guī)?,評審專家
國家自然科學基金與廣東省自然科學基金評審專家?guī)斐蓡T
主持項目:
先后主持國家自然科學基金青年基金、廣東省自然科學基金面上項目(3項),、廣東省醫(yī)學科研基金,、廣東省教育廳特色創(chuàng)新項目、佛山科學技術學院動物新發(fā)疫病防控重點實驗室開放基金,、佛山科學技術學院高層次人才啟動基金和佛山市博士后啟動基金等多項研究基金,;參與多項國自然基金與美國國立衛(wèi)生研究院基金項目。
近年部分論文:
1. Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J, Yu H, Liu Q, Huang S. 2024. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol 10.1128/jvi.00248-24.
2. Wen F, Li L, Zhao N, Chiang MJ, Xie H, Cooley J, Webby R, Wang PG, Wan XF. 2018. A Y161F Hemagglutinin Substitution Increases Thermostability and Improves Yields of 2009 H1N1 Influenza A Virus in Cells. J Virol 92.(2):e01621-17.
3. Wen F, Blackmon S, Olivier AK, Li L, Guan M, Sun H, Wang PG, Wan XF. 2018. Mutation W222L at the Receptor Binding Site of Hemagglutinin Could Facilitate Viral Adaption from Equine Influenza A(H3N8) Virus to Dogs. J Virol 92(18):e01115-18.
4. Guo J, He J, Liang Z, Huang S, Wen F. 2024. Birds as reservoirs: unraveling the global spread of Gammaand Deltacoronaviruses. mBio 10.1128/mbio.02324-24.
5. Gao C, Wen F, Guan M, Hatuwal B, Li L, Praena B, Tang CY, Zhang J, Luo F, Xie H, Webby R, Tao YJ, Wan XF. 2024. MAIVeSS: streamlined selection of antigenically matched, high-yield viruses for seasonal influenza vaccine production. Nat Commun 15:1128.
6. Yan Z, Li Y, Huang S, Wen F. 2023. Global distribution, receptor binding, and cross-species transmission of H6 influenza viruses: risks and implications for humans. J Virol 97:e0137023.
7. Zhang X, Chen G, Liu R, Guo J, Mei K, Qin L, Li Z, Yuan S, Huang S, Wen F. 2024. Identification, pathological, and genomic characterization of novel goose reovirus associated with liver necrosis in geese, China. Poult Sci 103:103269.
8. Wen F, Wang C, Guo J, Yu H, Yuan S, Li Y, Li Z, Huang S, Liang Z. 2024. Development and application of a triplex real-time PCR assay for the detection of H3, H4, and H5 subtypes of avian influenza virus. Poult Sci 103:103333.
9. Liu J, Liang Z, Sun W, Hua W, Huang S, Wen F. The H4 subtype of avian influenza virus: a review of its historical evolution, global distribution, adaptive mutations and receptor binding properties. Poult Sci. 2024 Aug;103(8):103913.
10. Wen F, Chen G, Guo J, Guan M, Li Z, Yu H, Li J, Liu Q, Huang S. 2023. Identification of a duck H9N2 influenza virus possessing tri-basic hemagglutinin cleavage sites genetically close to the human H9N2 isolates in China, 2022. J Infect 86:e153-e155.
11. Liu L, Chen G, Huang S, Wen F. 2023. Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research Advances. Virulence 14:2235459.
12. Yuan S, Cheng Q, Guo J, Li Z, Yang J, Wang C, Liang Z, Zhang X, Yu H, Li Y, Huang S, Wen F. 2022. Detection and genetic characterization of novel infectious bronchitis viruses from recent outbreaks in broiler and layer chicken flocks in southern China, 2021. Poult Sci 101:102082.
13. Wen F, Wan XF. 2019. Influenza Neuraminidase: Underrated Role in Receptor Binding. Trends Microbiol 27:477-479.
14. Wen F, Zhang X, Guo J, Liang Z, Cheng Q, Wang C, Yu H, Du Y, Huang S, Li J, Li Y. 2022. Emergence of H3N8 avian influenza viruses possessing tri-basic hemagglutinin cleavage sites in China. J Infect 85:e112-e114.
15. Wang SY, Wen F, Yu LX, Wang J, Wang MZ, Yan JC, Zhou YJ, Tong W, Shan TL, Li GX, Zheng H, Liu CL, Kong N, Tong GZ, Yu H. 2022. Potential Threats to Human Health from Eurasian Avian-Like Swine Influenza A(H1N1) Virus and Its Reassortants. Emerg Infect Dis 28:1489-1493.
16. Guo J, Wang C, Huang S, Wen F. Letter to the editor: Sequencing bias for residue 28 of the neuraminidase of the recent highly pathogenic avian influenza virus A(H5N8). Euro Surveill. 2021 Sep;26(36):2100829. doi: 10.2807/1560-7917.
17. Yang J, Li Y, Guo J, Luo K, Yu H, Chen Y, Li A, Yuan S, El-Ashram S, Huang S, Wen F. 2021. Genetic characterization of an H5N6 avian influenza virus from chickens in Guangdong, China. J Infect 82:414-451.
18. Guo J, Yu H, Yang J, Li Y, Zhang X, Mei K, Chi S, Yuan S, Liu H, El-Ashram S, Huang S, Wen F. 2021. Weighted gene co-expression network analysis revealed host transcriptional response to H1N1 influenza A virus infection. J Infect 82:e4-e7.
19. Guo J, Yu H, Wang C, Yuan S, Sun H, Yang J, Cheng Q, Luo K, Li Y, Li Z, Liu Q, Huang S, Wen F. 2021. Re-emergence of highly pathogenic avian influenza A(H5N8) virus in domestic Goose, China. J Infect 83:709-737.
20. Wen F, Yu H, Guo J, Li Y, Luo K, Huang S. 2020. Identification of the hyper-variable genomic hotspot for the novel coronavirus SARS-CoV-2. J Infect 80:671-693.
21. Wen F, Li W, Guo J, Yang J, Zhang X, Mei K, Liu H, El-Ashram S, Luo K, Yuan S, Chi S, Huang S. 2020. Genetic characterization of a novel genotype H9N2 avian influenza virus from chicken in South China. J Infect 81:816-846.
22. Wen F, Huang S, Guo J. 2020. Egg adaptive mutation patterns of H3N2 human influenza A viruses. J Infect 80:232-254.
23. Wang XH, Gong XQ, Wen F, Ruan BY, Yu LX, Liu XM, Wang Q, Wang SY, Wang J, Zhang YF, Zhou YJ, Shan TL, Tong W, Zheng H, Kong N, Yu H, Tong GZ. 2020. The role of PA-X C-terminal 20 residues of classical swine influenza virus in its replication and pathogenicity. Vet Microbiol 251:108916.
24. Guo J, Huang S, Wen F. 2020. Identification of coevolution sites and evolution history for neuraminidase of human influenza A viruses. J Infect 80:232-254.
25. Wen F, Guo J, Huang S. 2019. A meta-analysis identified genes responsible for distinct immune responses to trivalent inactivated and live attenuated influenza vaccines. J Cell Physiol 234:5196-5202.
26. Ruan BY, Wen F, Gong XQ, Liu XM, Wang Q, Yu LX, Wang SY, Zhang P, Yang HM, Shan TL, Zheng H, Zhou YJ, Tong W, Gao F, Tong GZ, Yu H. 2018. Protective efficacy of a high-growth reassortant H1N1 influenza virus vaccine against the European Avian-like H1N1 swine influenza virus in mice and pigs. Vet Microbiol 222:75-84.
27. Sun H, Blackmon S, Yang G, Waters K, Li T, Tangwangvivat R, Xu Y, Shyu D, Wen F, Cooley J, Senter L, Lin X, Jarman R, Hanson L, Webby R, Wan XF. 2017. Zoonotic Risk, Pathogenesis, and Transmission of Avian-Origin H3N2 Canine Influenza Virus. J Virol 91(21):e00637-17.
28. Guan M, Olivier AK, Lu X, Epperson W, Zhang X, Zhong L, Waters K, Mamaliger N, Li L, Wen F, Tao YJ, DeLiberto TJ, Wan XF. 2022. The Sialyl Lewis X Glycan Receptor Facilitates Infection of Subtype H7 Avian Influenza A Viruses. J Virol 96:e0134422.
29. Han L, Li L, Wen F, Zhong L, Zhang T, Wan XF. 2019. Graph-guided multi-task sparse learning model: a method for identifying antigenic variants of influenza A(H3N2) virus. Bioinformatics 35:77-87.
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